S1PR5

S1PR5
Identifiers
Aliases	S1PR5, EDG8, Edg-8, S1P5, SPPR-1, SPPR-2, sphingosine-1-phosphate receptor 5
External IDs	OMIM: 605146; MGI: 2150641; HomoloGene: 11031; GeneCards: S1PR5; OMA:S1PR5 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	10,517,931 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	21,159,739 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; C1 segment; ; internal globus pallidus; ; inferior ganglion of vagus nerve; ; corpus callosum; ; substantia nigra; ; skin of arm; ; subthalamic nucleus; ; blood; ; putamen;
	Top expressed in
	lumbar subsegment of spinal cord; ; substantia nigra; ; motor neuron; ; deep cerebellar nuclei; ; conjunctival fornix; ; lateral geniculate nucleus; ; anterior horn of spinal cord; ; cornea; ; pontine nuclei; ; globus pallidus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sphingosine-1-phosphate receptor activity; G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	regulation of neuron differentiation; sphingosine-1-phosphate receptor signaling pathway; signal transduction; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	53637
	94226
	ENSG00000180739
	ENSMUSG00000045087
	Q9H228
	Q91X56
	NM_030760; NM_001166215
	NM_053190
	NP_001159687; NP_110387
	NP_444420
	Wikidata
View/Edit Human	View/Edit Mouse

Sphingosine-1-phosphate receptor 5 also known as S1PR5 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P₅.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000180739 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000045087 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: S1PR5 Sphingosine-1-phosphate receptor 5".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000180739 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000045087 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: S1PR5 Sphingosine-1-phosphate receptor 5".

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