SEPT7

SEPTIN7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2QAG, 3T5D, 3TW4
Identifiers
Aliases	SEPTIN7, CDC10, CDC3, NBLA02942, SEPT7A, septin 7, SEPT7
External IDs	OMIM: 603151; MGI: 1335094; HomoloGene: 1354; GeneCards: SEPTIN7; OMA:SEPTIN7 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	35,907,110 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	25,219,867 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; subthalamic nucleus; ; inferior ganglion of vagus nerve; ; external globus pallidus; ; occipital lobe; ; ventricular zone; ; prefrontal cortex; ; primary visual cortex; ; Achilles tendon; ; endothelial cell;
	Top expressed in
	atrioventricular valve; ; dermis; ; prefrontal cortex; ; Gonadal ridge; ; left lung lobe; ; calvaria; ; optic nerve; ; nucleus accumbens; ; deep cerebellar nuclei; ; umbilical cord;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP binding; structural molecule activity; protein binding; identical protein binding; cadherin binding; GTPase activity; molecular adaptor activity;
Cellular component	cytosol; cell projection; spindle; cilium; septin complex; stress fiber; chromosome; midbody; apical plasma membrane; axoneme; cleavage furrow; chromosome, centromeric region; cytoskeleton; extracellular exosome; nucleus; kinetochore; cytoplasm; sperm annulus; non-motile cilium; septin ring; microtubule cytoskeleton; motile cilium;
Biological process	cilium assembly; protein heterooligomerization; cytokinesis; regulation of embryonic cell shape; cell division; positive regulation of non-motile cilium assembly; cell cycle; spermatogenesis; cell differentiation; negative regulation of cell migration; positive regulation of apoptotic process; cytoskeleton-dependent cytokinesis; negative regulation of G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	989
	235072
	ENSG00000122545
	ENSMUSG00000001833
	Q16181
	O55131
	NM_001011553; NM_001242956; NM_001788; NM_001363715; NM_001375299
	NM_001205367; NM_009859; NM_001359736; NM_001359737; NM_001359738
	NP_001011553; NP_001229885; NP_001779; NP_001350644; NP_001362228
	NP_001192296; NP_033989; NP_001346665; NP_001346666; NP_001346667
	Wikidata
View/Edit Human	View/Edit Mouse

Septin-7 is a protein that in humans is encoded by the SEPT7 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000122545 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001833 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nakatsuru S, Sudo K, Nakamura Y (July 1994). "Molecular cloning of a novel human cDNA homologous to CDC10 in Saccharomyces cerevisiae". Biochemical and Biophysical Research Communications. 202 (1): 82–7. doi:10.1006/bbrc.1994.1896. PMID 8037772.
^ "Entrez Gene: SEPT7 septin 7".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000122545 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000001833 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8037772-5] Nakatsuru S, Sudo K, Nakamura Y (July 1994). "Molecular cloning of a novel human cDNA homologous to CDC10 in Saccharomyces cerevisiae". Biochemical and Biophysical Research Communications. 202 (1): 82–7. doi:10.1006/bbrc.1994.1896. PMID 8037772.

[entrez-6] "Entrez Gene: SEPT7 septin 7".

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