SERPINB7

SERPINB7
Identifiers
Aliases	SERPINB7, MEGSIN, PPKN, TP55, serpin family B member 7
External IDs	OMIM: 603357; MGI: 2151053; HomoloGene: 68363; GeneCards: SERPINB7; OMA:SERPINB7 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	63,805,376 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	107,380,419 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; skin of leg; ; human penis; ; skin of abdomen; ; skin of thigh; ; skin of hip; ; epithelium of nasopharynx; ; vulva; ; testicle; ; bronchial epithelial cell;
	Top expressed in
	skin of external ear; ; umbilical cord; ; skin of abdomen; ; skin of back; ; olfactory epithelium; ; lip; ; esophagus; ; condyle; ; fossa; ; cervix;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase inhibitor activity; serine-type endopeptidase inhibitor activity;
Cellular component	cytoplasm; extracellular space;
Biological process	positive regulation of collagen biosynthetic process; positive regulation of transforming growth factor beta1 production; negative regulation of peptidase activity; positive regulation of glomerular mesangial cell proliferation; positive regulation of platelet-derived growth factor production; negative regulation of endopeptidase activity;
	Sources:Amigo / QuickGO
Orthologs
	8710
	116872
	ENSG00000166396
	ENSMUSG00000067001
	O75635
	Q9D695
	NM_001040147; NM_001261830; NM_001261831; NM_003784
	NM_027548
	NP_001035237; NP_001248759; NP_001248760; NP_003775
	NP_081824
	Wikidata
View/Edit Human	View/Edit Mouse

Serpin B7 is a protein that in humans is encoded by the SERPINB7 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166396 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000067001 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166396 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000067001 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7".

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