SET domain

SET
structure and substrate of a histone H3 lysine methyltransferase from Paramecium bursaria chlorella virus 1
Identifiers
SymbolSET
PfamPF00856
InterProIPR001214
SMARTSM0468
SCOP21ml9 / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

The SET domain is a protein domain that typically has methyltransferase activity. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived [Su(var)3-9, Enhancer-of-zeste and Trithorax].