SIN3B

SIN3B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1E91, 1PD7, 2CR7, 2CZY, 2F05
Identifiers
Aliases	SIN3B, Paired amphipathic helix protein Sin3b, SIN3 transcription regulator family member B
External IDs	OMIM: 607777; MGI: 107158; HomoloGene: 81810; GeneCards: SIN3B; OMA:SIN3B - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	16,880,353 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	73,484,829 bp
RNA expression pattern
	Top expressed in
	body of uterus; ; right uterine tube; ; right ovary; ; left ovary; ; canal of the cervix; ; right lung; ; gastric mucosa; ; left uterine tube; ; left testis; ; sural nerve;
	Top expressed in
	Gonadal ridge; ; Paneth cell; ; internal carotid artery; ; external carotid artery; ; fossa; ; renal corpuscle; ; epithelium of lens; ; condyle; ; endocardial cushion; ; medullary collecting duct;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transcription corepressor activity; histone deacetylase activity; chromatin binding; protein binding;
Cellular component	cytoplasm; X chromosome; Y chromosome; autosome; Sin3 complex; nucleoplasm; XY body; nucleus; chromatin;
Biological process	regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; negative regulation of transcription, DNA-templated; histone deacetylation; regulation of lipid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	23309
	20467
	ENSG00000127511
	ENSMUSG00000031622
	O75182
	Q62141
	NM_001297595; NM_001297597; NM_015260
	NM_001113248; NM_009188
	NP_001284524; NP_001284526; NP_056075
	NP_001106719; NP_033214
	Wikidata
View/Edit Human	View/Edit Mouse

Paired amphipathic helix protein Sin3b is a protein that in humans is encoded by the SIN3B gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000127511 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031622 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jun 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
^ "Entrez Gene: SIN3B SIN3 homolog B, transcription regulator (yeast)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000127511 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031622 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9734811-5] Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jun 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.

[entrez-6] "Entrez Gene: SIN3B SIN3 homolog B, transcription regulator (yeast)".

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