SLAMF1

SLAMF1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSLAMF1, CD150, CDw150, SLAM, signaling lymphocytic activation molecule family member 1
External IDsOMIM: 603492; MGI: 1351314; HomoloGene: 48162; GeneCards: SLAMF1; OMA:SLAMF1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003037
NM_001330754

NM_013730
NM_001360898

RefSeq (protein)

NP_001317683
NP_003028

NP_038758
NP_001347827

Location (UCSC)Chr 1: 160.61 – 160.65 MbChr 1: 171.59 – 171.63 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Signaling lymphocytic activation molecule 1 is a protein that in humans is encoded by the SLAMF1 gene.[5][6] Recently SLAMF1 has also been designated CD150 (cluster of differentiation 150).

SLAMF1 belongs to the signaling lymphocytic activation molecule family. As other receptors from this family, SLAMF1 is expressed in different types of hematopoietic cells and it plays a role in the regulation of the immune system.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000117090Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015316Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Cocks BG, Chang CC, Carballido JM, Yssel H, de Vries JE, Aversa G (July 1995). "A novel receptor involved in T-cell activation". Nature. 376 (6537): 260–263. Bibcode:1995Natur.376..260C. doi:10.1038/376260a0. PMID 7617038. S2CID 4319295.
  6. ^ "Entrez Gene: SLAMF1 signaling lymphocytic activation molecule family member 1".
  7. ^ Gordiienko I, Shlapatska L, Kovalevska L, Sidorenko SP (July 2019). "SLAMF1/CD150 in hematologic malignancies: Silent marker or active player?". Clinical Immunology. 204: 14–22. doi:10.1016/j.clim.2018.10.015. PMID 30616923. S2CID 58586790.