SUPT5H

SUPT5H
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DO3, 2E6Z, 2E70, 3H7H, 4L1U
Identifiers
Aliases	SUPT5H, SPT5, SPT5H, Tat-CT1, SPT5 homolog, DSIF elongation factor subunit
External IDs	OMIM: 602102; MGI: 1202400; HomoloGene: 2384; GeneCards: SUPT5H; OMA:SUPT5H - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	39,476,670 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	28,038,171 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; anterior pituitary; ; sural nerve; ; right hemisphere of cerebellum; ; right lobe of thyroid gland; ; right uterine tube; ; left lobe of thyroid gland; ; apex of heart; ; right frontal lobe;
	Top expressed in
	adrenal gland; ; Gonadal ridge; ; internal carotid artery; ; external carotid artery; ; fossa; ; crypt of lieberkuhn of small intestine; ; lacrimal gland; ; tail of embryo; ; vestibular membrane of cochlear duct; ; motor neuron;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein heterodimerization activity; enzyme binding; chromatin binding; RNA binding; DNA binding; mRNA binding;
Cellular component	nucleoplasm; DSIF complex; nucleus;
Biological process	chromatin remodeling; negative regulation of mRNA polyadenylation; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; transcription elongation from RNA polymerase II promoter; regulation of DNA-templated transcription, elongation; negative regulation of transcription by RNA polymerase II; 7-methylguanosine mRNA capping; transcription by RNA polymerase II; response to organic substance; transcription, DNA-templated; negative regulation of DNA-templated transcription, elongation; positive regulation of DNA-templated transcription, elongation; positive regulation of macroautophagy; DNA-templated transcription, elongation; single stranded viral RNA replication via double stranded DNA intermediate; positive regulation of viral transcription; cell cycle; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	6829
	20924
	ENSG00000196235
	ENSMUSG00000003435
	O00267
	O55201
NM_001111020; NM_001130824; NM_001130825; NM_003169; NM_001319990;
	NM_001319991
	NM_013676
NP_001104490; NP_001124296; NP_001124297; NP_001306919; NP_001306920;
	NP_003160
	NP_038704
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription elongation factor SPT5 is a protein that in humans is encoded by the SUPT5H gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196235 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003435 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chiang PW, Fogel E, Jackson CL, Lieuallen K, Lennon G, Qu X, Wang SQ, Kurnit DM (Dec 1996). "Isolation, sequencing, and mapping of the human homologue of the yeast transcription factor, SPT5". Genomics. 38 (3): 421–4. doi:10.1006/geno.1996.0646. PMID 8975720.
^ "Entrez Gene: SUPT5H Suppressor of Ty 5 homolog (S. cerevisiae)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000196235 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000003435 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8975720-5] Chiang PW, Fogel E, Jackson CL, Lieuallen K, Lennon G, Qu X, Wang SQ, Kurnit DM (Dec 1996). "Isolation, sequencing, and mapping of the human homologue of the yeast transcription factor, SPT5". Genomics. 38 (3): 421–4. doi:10.1006/geno.1996.0646. PMID 8975720.

[6] "Entrez Gene: SUPT5H Suppressor of Ty 5 homolog (S. cerevisiae)".

[1]

[2]

[3]

[4]

[5]

[6]