Sextus Claudius Petronius Probus (fl. 358–390) was a leading Roman aristocrat of the later 4th century AD, renowned for his wealth, power and social connections. The son of the consul Petronius Probinus, he married Anicia Faltonia Proba and had two sons. He had a successful political career, becoming praefectus urbanus, Proconsul of Africa, four times praetorian prefect, and consul alongside the emperor Gratian. His grandson and great-grandson went on to become emperor.