31°12′37″N 121°27′19″E / 31.210341°N 121.455366°E
| Shanghai No.2 High School | |
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| Location | |
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200 Yongkang Road, Xuhui District 1 Wuben Road, Minhang District Shanghai | |
| Information | |
| Former name | Wu Pen Girls' School (务本女塾); Huaijiu Junior High School for Girls (怀久女子中学); Shanghai No.2 Girls' High School (上海市第二女子中学) |
| Type | Public School, Shanghai Municipal Demonstrative High School |
| Motto | 勤(Diligence), 樸(Modesty), 勇(Bravery), 誠(Honesty) |
| Founded | 1902 |
| Founder | Wu Xin (吴馨) |
| Sister school | Needham High School; Wittelsbacher-Realschule Aichach |
| Principal | Wang Minzheng (王民政) |
| Faculty | 140+ |
| Grades | 6–12 |
| Gender | co-ed |
| Enrollment | 1440+ |
| Colour(s) | Red, white |
| Alumni | Yao Ming, Hu Ge, Zuo Yi, Xu Zheng, Neil Shen |
| Website | http://www.shiers.cn |
Shanghai No. 2 High School (simplified Chinese: 上海市第二中学; traditional Chinese: 上海市第二中學) is a public secondary school located in Shanghai, China.