Sialidase-4

NEU4
Identifiers
Aliases	NEU4, neuraminidase 4
External IDs	OMIM: 608527; MGI: 2661364; HomoloGene: 15433; GeneCards: NEU4; OMA:NEU4 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	241,817,413 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	93,956,056 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; right lobe of liver; ; substantia nigra; ; duodenum; ; temporal lobe; ; amygdala; ; hippocampus proper; ; hypothalamus; ; putamen; ; anterior cingulate cortex;
	Top expressed in
	striatum of neuraxis; ; primary visual cortex; ; Cortex of frontal lobe; ; hypothalamus; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; hippocampus proper; ; olfactory bulb;
	More reference expression data
	n/a
Gene ontology
Molecular function	exo-alpha-(2->6)-sialidase activity; exo-alpha-(2->8)-sialidase activity; hydrolase activity, acting on glycosyl bonds; protein binding; exo-alpha-(2->3)-sialidase activity; hydrolase activity; exo-alpha-sialidase activity;
Cellular component	organelle inner membrane; membrane; lysosomal lumen; lysosome; cytoplasm; intracellular membrane-bounded organelle;
Biological process	glycosphingolipid metabolic process; lipid metabolism; lipid catabolic process; glycoprotein catabolic process; oligosaccharide catabolic process; metabolism; ganglioside catabolic process; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	129807
	241159
	ENSG00000204099; ENSG00000277926
	ENSMUSG00000034000
	Q8WWR8
	Q8BZL1
	NM_080741; NM_001167599; NM_001167600; NM_001167601; NM_001167602
	NM_173772; NM_001310769
NP_001161071; NP_001161072; NP_001161073; NP_001161074; NP_542779;
	NP_001161071.1; NP_001161072.1; NP_001161073.1; NP_001161074.1
	NP_001297698; NP_776133
	Wikidata
View/Edit Human	View/Edit Mouse

Sialidase-4 is an enzyme that in humans is encoded by the NEU4 gene.^[5]

^ ^a ^b ^c ENSG00000277926 GRCh38: Ensembl release 89: ENSG00000204099, ENSG00000277926 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034000 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: NEU4 sialidase 4".

[refGRCh38Ensembl-1] ENSG00000277926 GRCh38: Ensembl release 89: ENSG00000204099, ENSG00000277926 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034000 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: NEU4 sialidase 4".

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