Sleep-related hypermotor epilepsy

Sleep-related hypermotor epilepsy
SpecialtyNeurology

Sleep-related hypermotor epilepsy (SHE), previously known as nocturnal frontal lobe epilepsy, is a form of focal epilepsy characterized by seizures which arise during sleep. The seizures are most typically characterized by complex motor behaviors. It is a relatively uncommon form of epilepsy that constitutes approximately 9-13% of cases.[1][2][3] This disorder is associated with cognitive impairment in at least half of patients as well as excessive daytime sleepiness due to poor sleep quality.[4] This disorder is sometimes misdiagnosed as a non-epileptic sleep disorder. There are many potential causes of SHE including genetic, acquired injuries and structural abnormalities.[5]

  1. ^ Thomas, R. H.; King, W. H.; Johnston, J. A.; Smith, P. E. M. (2010-02-01). "Awake seizures after pure sleep-related epilepsy: a systematic review and implications for driving law". Journal of Neurology, Neurosurgery & Psychiatry. 81 (2): 130–135. doi:10.1136/jnnp.2009.181438. ISSN 0022-3050. PMID 20145025. S2CID 9051378.
  2. ^ Provini, F. (1999-06-01). "Nocturnal frontal lobe epilepsy: A clinical and polygraphic overview of 100 consecutive cases". Brain. 122 (6): 1017–1031. doi:10.1093/brain/122.6.1017. ISSN 1460-2156. PMID 10356056.
  3. ^ Menghi, Veronica; Bisulli, Francesca; Tinuper, Paolo; Nobili, Lino (2018). "Sleep-related hypermotor epilepsy: prevalence, impact and management strategies". Nature and Science of Sleep. 10: 317–326. doi:10.2147/NSS.S152624. ISSN 1179-1608. PMC 6186898. PMID 30349413.
  4. ^ Asioli, Gian Maria; Rossi, Simone; Bisulli, Francesca; Licchetta, Laura; Tinuper, Paolo; Provini, Federica (2020-01-30). "Therapy in Sleep-Related Hypermotor Epilepsy (SHE)". Current Treatment Options in Neurology. 22 (1): 1. doi:10.1007/s11940-020-0610-1. ISSN 1092-8480. PMID 31997091. S2CID 210949795.
  5. ^ Bisulli, Francesca; Licchetta, Laura; Tinuper, Paolo (2019-07-17). "Sleep related hyper motor epilepsy (SHE): a unique syndrome with heterogeneous genetic etiologies". Sleep Science and Practice. 3 (1): 3. doi:10.1186/s41606-019-0035-5. ISSN 2398-2683. S2CID 198921976.