| |
| |
| Names | |
|---|---|
| Pronunciation | /ˌsoʊdiəm ˈflʊəraɪd/[1] |
| IUPAC name
Sodium fluoride
| |
| Other names
Florocid
| |
| Identifiers | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.028.789 |
| EC Number |
|
| KEGG | |
PubChem CID
|
|
| RTECS number |
|
| UNII | |
| UN number | 1690 |
CompTox Dashboard (EPA)
|
|
| |
| Properties | |
| NaF | |
| Molar mass | 41.988173 g/mol |
| Appearance | White to greenish solid |
| Odor | odorless |
| Density | 2.558 g/cm3 |
| Melting point | 993 °C (1,819 °F; 1,266 K) |
| Boiling point | 1,704 °C (3,099 °F; 1,977 K) |
| 36.4 g/L (0 °C); 40.4 g/L (20 °C); 50.5 g/L (100 °C)[2] | |
| Solubility | slightly soluble in HF, ammonia negligible in alcohol, acetone, SO2, dimethylformamide |
| Vapor pressure | 1 mmHg @ 1077 °C[3] |
| Acidity (pKa) | 3,20 (weak base, see HF) |
| −16.4·10−6 cm3/mol | |
Refractive index (nD)
|
1.3252 |
| Structure | |
| Cubic | |
a = 462 pm
| |
| Octahedral | |
| Thermochemistry | |
Heat capacity (C)
|
46.82 J/(mol K) |
Std molar
entropy (S⦵298) |
51.3 J/(mol K) |
Std enthalpy of
formation (ΔfH⦵298) |
-573.6 kJ/mol |
Gibbs free energy (ΔfG⦵)
|
-543.3 kJ/mol |
| Pharmacology | |
| A01AA01 (WHO) A12CD01 (WHO), V09IX06 (WHO) (18F) | |
| Hazards | |
| GHS labelling: | |
  
| |
| Danger | |
| H301, H315, H319, H335[4] | |
| NFPA 704 (fire diamond) | |
| Flash point | Non-flammable |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
|
52–130 mg/kg (oral in rats, mice, rabbits)[6] |
| NIOSH (US health exposure limits): | |
PEL (Permissible)
|
TWA 2.5 mg/m3[5] |
REL (Recommended)
|
TWA 2.5 mg/m3[5] |
IDLH (Immediate danger)
|
250 mg/m3 (as F)[5] |
| Safety data sheet (SDS) | [4] |
| Related compounds | |
Other anions
|
Sodium chloride Sodium bromide Sodium iodide Sodium astatide |
Other cations
|
Lithium fluoride Potassium fluoride Rubidium fluoride Caesium fluoride Francium fluoride |
Related compounds
|
TASF reagent |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
Sodium fluoride (NaF) is an inorganic compound with the formula NaF. It is a colorless or white solid that is readily soluble in water. It is used in trace amounts in the fluoridation of drinking water to prevent tooth decay, and in toothpastes and topical pharmaceuticals for the same purpose. In 2021, it was the 291st most commonly prescribed medication in the United States, with more than 600,000 prescriptions.[7][8] It is also used in metallurgy and in medical imaging.
- ^ Wells, John C. (2008), Longman Pronunciation Dictionary (3rd ed.), Longman, pp. 313 and 755, ISBN 978-1-4058-8118-0. According to this source, an alternative pronunciation of the second word is /ˈflɔːraɪd/ and, in the UK, also /ˈfluːəraɪd/.
- ^ Haynes, William M., ed. (2011). CRC Handbook of Chemistry and Physics (92nd ed.). CRC Press. p. 5.194. ISBN 978-1-4398-5511-9.
- ^ Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 10th ed. Volumes 1–3 New York, NY: John Wiley & Sons Inc., 1999., p. 3248
- ^ a b Sigma-Aldrich Co., Sodium Fluoride.
- ^ a b c NIOSH Pocket Guide to Chemical Hazards. "#0563". National Institute for Occupational Safety and Health (NIOSH).
- ^ Martel, B.; Cassidy, K. (2004), Chemical Risk Analysis: A Practical Handbook, Butterworth–Heinemann, p. 363, ISBN 978-1-903996-65-2
- ^ "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
- ^ "Sodium Fluoride – Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.