Somatostatin receptor 1

SSTR1
Identifiers
Aliases	SSTR1, SRIF-2, SS-1-R, SS1-R, SS1R, Somatostatin receptor 1
External IDs	OMIM: 182451; MGI: 98327; HomoloGene: 820; GeneCards: SSTR1; OMA:SSTR1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	38,213,067 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	58,261,230 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; jejunal mucosa; ; Brodmann area 46; ; duodenum; ; prefrontal cortex; ; middle temporal gyrus; ; pars reticulata; ; pars compacta; ; Brodmann area 23; ; dorsolateral prefrontal cortex;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; embryo; ; superior frontal gyrus; ; primary visual cortex; ; ventromedial nucleus; ; anterior amygdaloid area; ; primary motor cortex; ; subiculum; ; dorsomedial hypothalamic nucleus; ; arcuate nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; neuropeptide binding; signal transducer activity; somatostatin receptor activity; peptide binding;
Cellular component	cytoplasm; integral component of membrane; membrane; plasma membrane; neuron projection; integral component of plasma membrane;
Biological process	glutamate receptor signaling pathway; somatostatin signaling pathway; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; cellular response to estradiol stimulus; cerebellum development; spermatogenesis; response to starvation; forebrain development; neuropeptide signaling pathway; signal transduction; negative regulation of cell population proliferation; cellular response to leukemia inhibitory factor; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	6751
	20605
	ENSG00000139874
	ENSMUSG00000035431
	P30872
	P30873
	NM_001049
	NM_009216
	NP_001040
	NP_033242
	Wikidata
View/Edit Human	View/Edit Mouse

Somatostatin receptor type 1 is a protein that in humans is encoded by the SSTR1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000139874 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035431 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (February 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics. 15 (2): 449–52. doi:10.1006/geno.1993.1088. PMID 8449518.
^ "Entrez Gene: SSTR1 somatostatin receptor 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000139874 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035431 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8449518-5] Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (February 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics. 15 (2): 449–52. doi:10.1006/geno.1993.1088. PMID 8449518.

[entrez-6] "Entrez Gene: SSTR1 somatostatin receptor 1".

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