Somatostatin receptor 3

SSTR3
Identifiers
Aliases	SSTR3, SS-3-R, SS3-R, SS3R, SSR-28, Somatostatin receptor 3
External IDs	OMIM: 182453; MGI: 98329; HomoloGene: 20285; GeneCards: SSTR3; OMA:SSTR3 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	37,212,477 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	78,428,885 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; islet of Langerhans; ; prefrontal cortex; ; right frontal lobe; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; occipital lobe; ; primary visual cortex; ; right testis; ; left testis;
	Top expressed in
	islet of Langerhans; ; lumbar subsegment of spinal cord; ; dentate gyrus of hippocampal formation granule cell; ; subdivision of hippocampus; ; primary motor cortex; ; Region I of hippocampus proper; ; primary visual cortex; ; hippocampus proper; ; superior frontal gyrus; ; prefrontal cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	neuropeptide binding; signal transducer activity; protein binding; somatostatin receptor activity; signaling receptor binding; G protein-coupled receptor activity; peptide binding;
Cellular component	cytoplasm; integral component of membrane; membrane; integral component of plasma membrane; cilium; neuron projection; plasma membrane; ciliary membrane; non-motile cilium;
Biological process	cell-cell signaling; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; cellular response to estradiol stimulus; cerebellum development; cellular response to glucocorticoid stimulus; spermatogenesis; response to starvation; hormone-mediated apoptotic signaling pathway; forebrain development; signal transduction; negative regulation of cell population proliferation; chemical synaptic transmission; somatostatin signaling pathway; neuropeptide signaling pathway; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	6753
	20607
	ENSG00000278195
	ENSMUSG00000044933
	P32745
	P30935
	NM_001051; NM_001278687
	NM_009218; NM_001356961
	NP_001042; NP_001265616
	NP_033244; NP_001343890
	Wikidata
View/Edit Human	View/Edit Mouse

Shekel Somatostatin receptor type 3 is a protein that in humans is encoded by the SSTR3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000278195 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044933 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (February 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics. 15 (2): 449–52. doi:10.1006/geno.1993.1088. PMID 8449518.
^ "Entrez Gene: SSTR3 somatostatin receptor 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000278195 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000044933 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8449518-5] Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (February 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics. 15 (2): 449–52. doi:10.1006/geno.1993.1088. PMID 8449518.

[entrez-6] "Entrez Gene: SSTR3 somatostatin receptor 3".

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