Somatostatin receptor 5

SSTR5
Identifiers
Aliases	SSTR5, SS-5-R, Somatostatin receptor 5
External IDs	MGI: 894282; HomoloGene: 20287; GeneCards: SSTR5; OMA:SSTR5 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	1,081,454 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	25,716,262 bp
RNA expression pattern
	Top expressed in
	right auricle; ; apex of heart; ; anterior pituitary; ; right adrenal cortex; ; left ventricle; ; Descending thoracic aorta; ; left adrenal cortex; ; ascending aorta; ; right coronary artery; ; metanephros;
	Top expressed in
	embryo; ; embryo; ; choroid plexus of fourth ventricle; ; soleus muscle; ; entorhinal cortex; ; superior frontal gyrus; ; primary motor cortex; ; superior colliculus; ; basal forebrain; ; striatum of neuraxis;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	neuropeptide binding; G protein-coupled receptor activity; signal transducer activity; somatostatin receptor activity; peptide binding;
Cellular component	integral component of membrane; neuron projection; plasma membrane; integral component of plasma membrane; membrane;
Biological process	positive regulation of cytokinesis; G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; glucose homeostasis; signal transduction; negative regulation of cell population proliferation; regulation of insulin secretion; somatostatin signaling pathway; chemical synaptic transmission; cellular response to glucocorticoid stimulus; neuropeptide signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	6755
	20609
	ENSG00000162009
	ENSMUSG00000050824
	P35346
	O08858
	NM_001053; NM_001172560; NM_001172572; NM_001172573
	NM_001191008; NM_011425
	NP_001044; NP_001166031
	NP_001177937; NP_035555
	Wikidata
View/Edit Human	View/Edit Mouse

Somatostatin receptor type 5 is a protein that in humans is encoded by the SSTR5 gene.^[5]

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR5 is a member of the superfamily of receptors having seven transmembrane segments.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000162009 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000050824 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Takeda J, Fernald AA, Yamagata K, Le Beau MM, Bell GI (Aug 1995). "Localization of human somatostatin receptor 5 gene (SSTR5) to chromosome band 16p13.3 by fluorescence in situ hybridization". Genomics. 26 (3): 638–9. doi:10.1016/0888-7543(95)80195-R. PMID 7607700.
^ "Entrez Gene: SSTR5 somatostatin receptor 5".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000162009 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000050824 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7607700-5] Takeda J, Fernald AA, Yamagata K, Le Beau MM, Bell GI (Aug 1995). "Localization of human somatostatin receptor 5 gene (SSTR5) to chromosome band 16p13.3 by fluorescence in situ hybridization". Genomics. 26 (3): 638–9. doi:10.1016/0888-7543(95)80195-R. PMID 7607700.

[entrez-6] "Entrez Gene: SSTR5 somatostatin receptor 5".

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