South Dakota Highway 46

Highway 46
Route of SD 46 (in red)
Route information
Maintained by SDDOT
Length	105.535 mi[1] (169.842 km)
Existed	1936–present
Major junctions
West end	US 18 / US 281 in Pickstown
Major intersections	I-29 in Beresford US 81 near Mayfield
East end	Iowa 10 at Iowa state line
Location
Country	United States
State	South Dakota
Counties	Charles Mix Bon Homme Yankton County Clay Turner Lincoln Union
Highway system
South Dakota State Trunk Highway System Interstate US State
← SD 45 → SD 47

South Dakota Highway 46 is a 105.535-mile (169.842 km) state highway in South Dakota, United States, that runs west to east across the southeastern part of the state. It begins at the junction of U.S. Highway 18 and U.S. Highway 281 in Pickstown, and runs due east to nearly the Iowa border, before curving south to cross the border and meeting Iowa Highway 10.