Spiruchostatin

Spiruchostatin A
Names
Preferred IUPAC name
(1S,4R,8S,12S,13R,21E)-12-Hydroxy-4-methyl-13-(propan-2-yl)-9-oxa-17,18-dithia-2,5,14-triazabicyclo[7.7.6]docos-21-ene-3,6,10,15-tetrone
Identifiers
3D model (JSmol)
UNII
  • CC(C)[C@H]1NC(=O)[C@H]2CSSCC\C=C\[C@H](CC(=O)N[C@H](C)C(=O)N2)OC(=O)C[C@@H]1O
Properties
C20H31N3O6S2
Molar mass 473.60 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Spiruchostatins are a group of chemical compounds isolated from Pseudomonas sp. as gene expression-enhancing substances. They possess novel bicyclic depsipeptides involving 4-amino-3-hydroxy-5-methylhexanoic acid and 4-amino-3-hydroxy-5-methylheptanoic acid residues.[1] The two main forms are spiruchostatin A and spiruchostatin B.

  1. ^ Masuoka, Y., Nagai, A., Shin-ya, K., Furihata, K., Nagai, K., Suzuki, K.-i.; et al. (2001). "Spiruchostatins A and B, novel gene expression-enhancing substances produced by Pseudomonas sp". Tetrahedron Lett. 42: 41–44. doi:10.1016/s0040-4039(00)01874-8.{{cite journal}}: CS1 maint: multiple names: authors list (link)