Look up spleen in Wiktionary, the free dictionary.
The spleen is an organ in the human body.
Spleen may also refer to:
- Spleen, poem by Baudelaire
- Spleen (Chinese medicine), an element of body function
- A French rapper/musician who sometimes performs with CocoRosie
- A character in Mystery Men
- "Spleen", a song by Staind from Dysfunction