Stress fiber

Stress Fiber
Stress Fiber
	Stress fibers - visualized via fluorescence micrograph of F-actin
Identifiers
MeSH	D022502
TH	H1.00.01.1.02033
	Anatomical terminology [edit on Wikidata]

Stress fibers are contractile actin bundles found in non-muscle cells.^[1] They are composed of actin (microfilaments) and non-muscle myosin I (NMMII), and also contain various crosslinking proteins, such as α-actinin, to form a highly regulated actomyosin structure within non-muscle cells.^[2] Stress fibers have been shown to play an important role in cellular contractility, providing force for a number of functions such as cell adhesion, migration and morphogenesis.

^ Kreis, Thomas E.; Birchmeier, Walter (November 1980). "Stress fiber sarcomeres of fibroblasts are contractile". Cell. 22 (2): 555–561. doi:10.1016/0092-8674(80)90365-7. PMID 6893813. S2CID 11435890.
^ Tojkander, S.; Gateva, G.; Lappalainen, P. (April 29, 2012). "Actin stress fibers - assembly, dynamics and biological roles". Journal of Cell Science. 125 (8): 1855–1864. doi:10.1242/jcs.098087. PMID 22544950.

[1] Kreis, Thomas E.; Birchmeier, Walter (November 1980). "Stress fiber sarcomeres of fibroblasts are contractile". Cell. 22 (2): 555–561. doi:10.1016/0092-8674(80)90365-7. PMID 6893813. S2CID 11435890.

[2] Tojkander, S.; Gateva, G.; Lappalainen, P. (April 29, 2012). "Actin stress fibers - assembly, dynamics and biological roles". Journal of Cell Science. 125 (8): 1855–1864. doi:10.1242/jcs.098087. PMID 22544950.

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