Subgranular zone

The subgranular zone (in rat brain). (A) Regions of the dentate gyrus: the hilus, subgranular zone (sgz), granule cell layer (GCL), and molecular layer (ML). Cells were stained for doublecortin (DCX), a protein expressed by neuronal precursor cells and immature neurons. (B) Closeup of subgranular zone, located between the hilus and GCL. From a paper by Charlotte A. Oomen, et al., 2009.

The subgranular zone (SGZ) is a brain region in the hippocampus where adult neurogenesis occurs. The other major site of adult neurogenesis is the subventricular zone (SVZ) in the brain.[1]

  1. ^ Ohira, Koji (2023). "Cortical adult neurogenesis and its biological implication". Clinical and Experimental Neuroimmunology. 14: 44–51. doi:10.1111/cen3.12652. ISSN 1759-1961. S2CID 236282146.