Sublabial administration

Sublabial administration, literally "under the lip", from Latin, refers to the pharmacological route of administration by which the active substance is placed between the lip and the gingiva (gum) to diffuse through the oral mucosa. Sublabial administration should not be confused with sublingual administration, which is under the tongue. The frenulum of the tongue may be irritated when in contact with corrosive materials but can be avoided with this route. It is usually used for medications such as glyceryl trinitrate, for example, in angina pectoris.^[1]