Sulfolobus tengchongensis spindle-shaped virus

Sulfolobus tengchongensis spindle-shaped virus
Electron micrograph of Sulfolobus infected with Sulfolobus virus STSV1. Bar = 1 μm.
Virus classification
Group:
Group I (dsDNA)
Order:
Unassigned
Family:
Bicaudaviridae
Genus:
not assigned
Species:
Sulfolobus tengchongensis spindle-shaped virus 1

Sulfolobus tengchongensis spindle-shaped virus 1 (STSV1) is a DNA virus of the family Bicaudaviridae. It infects the hyperthermophilic archaeon Sulfolobus tengchongensis which can be found in the volcanic area of Tengchong, Baoshan City, in western Yunnan province, People's Republic of China.[1][2]

In 2014, Sulfolobus tengchongensis spindle-shaped virus 2 (STSV2), a relative of STSV1, also infecting S. tengchongensis, has been reported.[3] Besides S. tengchongensis, STSV2 infects Sulfolobus islandicus REY15A. It has been demonstrated that STSV2 induces unprecedented gigantism of S. islandicus cells by blocking the expression of the cell division genes and arresting the cell cycle in the S phase.[4] The diameter of infected cells increases up to 20 times, resulting in 8,000-fold increase in volume compared to noninfected cells.[4]

  1. ^ Xiang X, Chen L, Huang X, Luo Y, She Q, Huang L (2005). "Sulfolobus tengchongensis spindle-shaped virus STSV1: virus-host interactions and genomic features". J. Virol. 79 (14): 8677–86. doi:10.1128/JVI.79.14.8677-8686.2005. PMC 1168784. PMID 15994761. Alternatively: PubMed, ResearchGate
  2. ^ Uniprot Taxonomy: Sulfolobus virus STSV1
  3. ^ Erdmann, S; Chen, B; Huang, X; Deng, L; Liu, C; Shah, SA; Le Moine Bauer, S; Sobrino, CL; Wang, H; Wei, Y; She, Q; Garrett, RA; Huang, L; Lin, L (January 2014). "A novel single-tailed fusiform Sulfolobus virus STSV2 infecting model Sulfolobus species". Extremophiles: Life Under Extreme Conditions. 18 (1): 51–60. doi:10.1007/s00792-013-0591-z. PMID 24163004. S2CID 16545086.
  4. ^ a b Liu, J; Cvirkaite-Krupovic, V; Baquero, DP; Yang, Y; Zhang, Q; Shen, Y; Krupovic, M (2021-04-13). "Virus-induced cell gigantism and asymmetric cell division in archaea". Proceedings of the National Academy of Sciences of the United States of America. 118 (15): e2022578118. Bibcode:2021PNAS..11822578L. doi:10.1073/pnas.2022578118. PMC 8054024. PMID 33782110.