Sultiame

Sultiame

Clinical data
Trade names	Ospolot
Other names	Sulthiame (AAN AU), sulthiame (USAN US)
AHFS/Drugs.com	International Drug Names
Pregnancy category	AU: D
Routes of administration	Oral
ATC code	N03AX03 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	100% (oral)
Protein binding	29%
Metabolism	Hepatic secretion
Elimination half-life	24 hours
Excretion	Fecal (10%) and renal (90%)
Identifiers
IUPAC name 4-(1,1-dioxothiazinan-2-yl)benzenesulfonamide
CAS Number	61-56-3 N
PubChem CID	5356
DrugBank	DB08329 Y
ChemSpider	5163 Y
UNII	I00Q766CZ2
KEGG	D01787 Y
ChEMBL	ChEMBL328560 Y
CompTox Dashboard (EPA)	DTXSID4023626
ECHA InfoCard	100.000.465
Chemical and physical data
Formula	C10H14N2O4S2
Molar mass	290.35 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=S2(=O)N(c1ccc(cc1)S(=O)(=O)N)CCCC2
InChI InChI=1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16) Y Key:HMHVCUVYZFYAJI-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Sultiame (or sulthiame) is a sulfonamide and inhibitor of the enzyme carbonic anhydrase. It is used as an anticonvulsant and in recent studies showed promise in reducing sleep disordered breathing and other symptoms of obstructive sleep apnea (OSA).