T-2 mycotoxin

T-2[1]
Names
IUPAC name
(2α,3α,4β,8α)-4,15-bis(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
Other names
T-2 Toxin
Fusariotoxin T 2
Insariotoxin
Mycotoxin T 2
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.040.255 Edit this at Wikidata
RTECS number
  • YD0100000
UNII
  • InChI=1S/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1 checkY
    Key: BXFOFFBJRFZBQZ-QYWOHJEZSA-N checkY
  • InChI=1/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1
    Key: BXFOFFBJRFZBQZ-QYWOHJEZBH
  • O=C(O[C@@H]4C(=C/[C@H]3O[C@H]2[C@]1(OC1)[C@]([C@H](OC(=O)C)[C@H]2O)([C@@]3(COC(=O)C)C4)C)\C)CC(C)C
Properties
C24H34O9
Molar mass 466.527 g·mol−1
Insoluble
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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T-2 mycotoxin is a trichothecene mycotoxin. It is a naturally occurring mold byproduct of Fusarium spp. fungus which is toxic to humans and other animals. The clinical condition it causes is alimentary toxic aleukia and a host of symptoms related to organs as diverse as the skin, airway, and stomach. Ingestion may come from consumption of moldy whole grains. T-2 can be absorbed through human skin.[2] Although no significant systemic effects are expected after dermal contact in normal agricultural or residential environments, local skin effects can not be excluded. Hence, skin contact with T-2 should be limited.

  1. ^ "T-2 Toxin: essential data". CBWInfo.com. Archived from the original on October 12, 2008.
  2. ^ Boonen J, Malysheva SV, Taevernier L, Diana Di Mavungu J, De Saeger S, De Spiegeleer B (November 2012). "Human skin penetration of selected model mycotoxins". Toxicology. 301 (1–3): 21–32. doi:10.1016/j.tox.2012.06.012. PMID 22749975.