TAS2R10

TAS2R10
Identifiers
Aliases	TAS2R10, T2R10, TRB2, taste 2 receptor member 10
External IDs	OMIM: 604791; MGI: 2681218; HomoloGene: 128355; GeneCards: TAS2R10; OMA:TAS2R10 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	10,826,358 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	131,667,026 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; Achilles tendon; ; endometrium; ; left adrenal cortex; ; corpus callosum; ; granulocyte; ; right ovary; ; stromal cell of endometrium; ; body of uterus; ; gastric mucosa;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; taste receptor activity; bitter taste receptor activity;
Cellular component	plasma membrane; membrane; integral component of membrane;
Biological process	detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction; response to stimulus; sensory perception of taste; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	50839
	387346
	ENSG00000272805; ENSG00000121318; ENSG00000277238
	ENSMUSG00000063478
	Q9NYW0
	Q7M722
	NM_023921
	NM_207019
	NP_076410
	NP_996902
	Wikidata
View/Edit Human	View/Edit Mouse

Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene.^[5]^[6]^[7] The protein is responsible for bitter taste recognition in mammals. It serves as a defense mechanism to prevent consumption of toxic substances which often have a characteristic bitter taste.^[8]

^ ^a ^b ^c ENSG00000121318, ENSG00000277238 GRCh38: Ensembl release 89: ENSG00000272805, ENSG00000121318, ENSG00000277238 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000063478 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (March 2000). "A novel family of mammalian taste receptors". Cell. 100 (6): 693–702. doi:10.1016/S0092-8674(00)80705-9. PMID 10761934. S2CID 14604586.
^ Matsunami H, Montmayeur JP, Buck LB (April 2000). "A family of candidate taste receptors in human and mouse". Nature. 404 (6778): 601–604. Bibcode:2000Natur.404..601M. doi:10.1038/35007072. PMID 10766242. S2CID 4336913.
^ "TAS2R10 taste receptor, type 2, member 10". Entrez Gene. U.S. National Library of Medicine.
^ Born S, Levit A, Niv MY, Meyerhof W, Behrens M (January 2013). "The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands". The Journal of Neuroscience. 33 (1): 201–213. doi:10.1523/JNEUROSCI.3248-12.2013. PMC 6618634. PMID 23283334.

[refGRCh38Ensembl-1] ENSG00000121318, ENSG00000277238 GRCh38: Ensembl release 89: ENSG00000272805, ENSG00000121318, ENSG00000277238 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000063478 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10761934-5] Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (March 2000). "A novel family of mammalian taste receptors". Cell. 100 (6): 693–702. doi:10.1016/S0092-8674(00)80705-9. PMID 10761934. S2CID 14604586.

[pmid10766242-6] Matsunami H, Montmayeur JP, Buck LB (April 2000). "A family of candidate taste receptors in human and mouse". Nature. 404 (6778): 601–604. Bibcode:2000Natur.404..601M. doi:10.1038/35007072. PMID 10766242. S2CID 4336913.

[entrez-7] "TAS2R10 taste receptor, type 2, member 10". Entrez Gene. U.S. National Library of Medicine.

[Born_2013-8] Born S, Levit A, Niv MY, Meyerhof W, Behrens M (January 2013). "The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands". The Journal of Neuroscience. 33 (1): 201–213. doi:10.1523/JNEUROSCI.3248-12.2013. PMC 6618634. PMID 23283334.

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