TCEP

TCEP
Skeletal formula of TCEP
Space-filling model of the TCEP molecule
Names
Preferred IUPAC name
3,3′,3′′-Phosphanetriyltripropanoic acid
Other names
TCEP
Tris(2-carboxyethyl)phosphine
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C9H15O6P/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15/h1-6H2,(H,10,11)(H,12,13)(H,14,15) ☒N
    Key: PZBFGYYEXUXCOF-UHFFFAOYSA-N ☒N
  • InChI=1/C9H15O6P/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15/h1-6H2,(H,10,11)(H,12,13)(H,14,15)
    Key: PZBFGYYEXUXCOF-UHFFFAOYAQ
  • OC(CCP(CCC(O)=O)CCC(O)=O)=O
Properties
C9H15O6P
Molar mass 250.187 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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TCEP (tris(2-carboxyethyl)phosphine) is a reducing agent frequently used in biochemistry and molecular biology applications. It is often prepared and used as a hydrochloride salt (TCEP-HCl) with a molecular weight of 286.65 gram/mol. It is soluble in water and available as a stabilized solution at neutral pH and immobilized onto an agarose support to facilitate removal of the reducing agent.