TEAD3

TEAD3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5EMW
Identifiers
Aliases	TEAD3, DTEF-1, ETFR-1, TEAD-3, TEAD5, TEF-5, TEF5, TEA domain transcription factor 3
External IDs	OMIM: 603170; MGI: 109241; HomoloGene: 81821; GeneCards: TEAD3; OMA:TEAD3 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	35,497,079 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	28,569,791 bp
RNA expression pattern
	Top expressed in
	muscle layer of sigmoid colon; ; gastric mucosa; ; body of uterus; ; left uterine tube; ; popliteal artery; ; tibial arteries; ; right coronary artery; ; thoracic aorta; ; ascending aorta; ; ectocervix;
	Top expressed in
	lip; ; genital tubercle; ; esophagus; ; trophoblast giant cell; ; ventricular zone; ; muscle of thigh; ; neural layer of retina; ; urethra; ; female urethra; ; molar;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; nucleus; transcription regulator complex;
Biological process	regulation of transcription by RNA polymerase II; female pregnancy; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-templated; hippo signaling; transcription, DNA-templated; asymmetric neuroblast division; positive regulation of transcription by RNA polymerase II; embryonic organ development;
	Sources:Amigo / QuickGO
Orthologs
	7005
	21678
	ENSG00000007866
	ENSMUSG00000002249
	Q99594
	P70210
	NM_003214; NM_001395214
	NM_001098226; NM_001204156; NM_011566
	NP_003205
	NP_001091696; NP_001191085; NP_035696
	Wikidata
View/Edit Human	View/Edit Mouse

Transcriptional enhancer factor TEF-5 is a protein that in humans is encoded by the TEAD3 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000007866 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000002249 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Jacquemin P, Depetris D, Mattei MG, Martial JA, Davidson I (Jan 1999). "Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis". Genomics. 55 (1): 127–9. doi:10.1006/geno.1998.5628. hdl:2268/13836. PMID 9889009.
^ Jacquemin P, Martial JA, Davidson I (May 1997). "Human TEF-5 is preferentially expressed in placenta and binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer". The Journal of Biological Chemistry. 272 (20): 12928–37. doi:10.1074/jbc.272.20.12928. PMID 9148898.
^ "Entrez Gene: TEAD3 TEA domain family member 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000007866 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000002249 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9889009-5] Jacquemin P, Depetris D, Mattei MG, Martial JA, Davidson I (Jan 1999). "Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis". Genomics. 55 (1): 127–9. doi:10.1006/geno.1998.5628. hdl:2268/13836. PMID 9889009.

[pmid9148898-6] Jacquemin P, Martial JA, Davidson I (May 1997). "Human TEF-5 is preferentially expressed in placenta and binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer". The Journal of Biological Chemistry. 272 (20): 12928–37. doi:10.1074/jbc.272.20.12928. PMID 9148898.

[entrez-7] "Entrez Gene: TEAD3 TEA domain family member 3".

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