TESK2

TESK2
Identifiers
Aliases	TESK2, testis-specific kinase 2, testis associated actin remodelling kinase 2
External IDs	OMIM: 604746; MGI: 2385204; HomoloGene: 5188; GeneCards: TESK2; OMA:TESK2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	45,491,163 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	116,663,153 bp
RNA expression pattern
	Top expressed in
	cartilage tissue; ; C1 segment; ; secondary oocyte; ; skin of abdomen; ; jejunal mucosa; ; skin of limb; ; skin of leg; ; duodenum; ; skin of arm; ; testicle;
	Top expressed in
	granulocyte; ; spermatid; ; lobe of prostate; ; sciatic nerve; ; utricle; ; seminiferous tubule; ; vestibular membrane of cochlear duct; ; left colon; ; stria vascularis; ; jejunum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; nucleotide binding; protein binding; ATP binding; metal ion binding; kinase activity; protein serine/threonine kinase activity; signal transducer activity;
Cellular component	nucleoplasm; nucleus; cytoplasm; nuclear body;
Biological process	protein phosphorylation; peptidyl-tyrosine phosphorylation; focal adhesion assembly; actin cytoskeleton organization; spermatogenesis; phosphorylation; intracellular signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	10420
	230661
	ENSG00000070759
	ENSMUSG00000033985
	Q96S53
	Q8VCT9
	NM_007170; NM_001320800
	NM_146151
	NP_001307729; NP_009101
	NP_666263
	Wikidata
View/Edit Human	View/Edit Mouse

Dual specificity testis-specific protein kinase 2 is an enzyme that in humans is encoded by the TESK2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000070759 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000033985 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Røsok O, Pedeutour F, Ree AH, Aasheim HC (October 1999). "Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis". Genomics. 61 (1): 44–54. doi:10.1006/geno.1999.5922. PMID 10512679.
^ "Entrez Gene: TESK2 testis-specific kinase 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000070759 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000033985 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10512679-5] Røsok O, Pedeutour F, Ree AH, Aasheim HC (October 1999). "Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis". Genomics. 61 (1): 44–54. doi:10.1006/geno.1999.5922. PMID 10512679.

[entrez-6] "Entrez Gene: TESK2 testis-specific kinase 2".

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