TGF beta Activation

Transforming growth factor beta (TGF-β) is a potent cell regulatory polypeptide homodimer of 25kD.^[1] It is a multifunctional signaling molecule with more than 40 related family members. TGF-β plays a role in a wide array of cellular processes including early embryonic development, cell growth, differentiation, motility, and apoptosis.^[2]

^ Roberts, A.B. and Sporn, M.B., 1990. The transforming growth factor βs. In: Sporn, M.B. and Roberts, A.B., Editors, 1990. Peptides, Growth Factors and Their Receptors Part I, Springer-Verlag, Berlin, pp. 419–472,
^ Yue, J; Mulder, KM (2001). "Transforming growth factor-beta signal transduction in epithelial cells". Pharmacol Ther. 91 (1): 1–34. doi:10.1016/s0163-7258(01)00143-7. PMID 11707292.

[1] Roberts, A.B. and Sporn, M.B., 1990. The transforming growth factor βs. In: Sporn, M.B. and Roberts, A.B., Editors, 1990. Peptides, Growth Factors and Their Receptors Part I, Springer-Verlag, Berlin, pp. 419–472,

[yue-2] Yue, J; Mulder, KM (2001). "Transforming growth factor-beta signal transduction in epithelial cells". Pharmacol Ther. 91 (1): 1–34. doi:10.1016/s0163-7258(01)00143-7. PMID 11707292.

[1]

[2]