TLN2

TLN2
Identifiers
AliasesTLN2, ILWEQ, talin 2
External IDsOMIM: 607349; MGI: 1917799; HomoloGene: 56692; GeneCards: TLN2; OMA:TLN2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015059
NM_001394547

NM_001081242
NM_027458

RefSeq (protein)

NP_055874

Location (UCSC)Chr 15: 62.39 – 62.84 MbChr 9: 67.12 – 67.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Talin-2 is a protein in humans that is encoded by the TLN2 gene. It belongs to the talin protein family. This gene encodes a protein related to talin-1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments. Talin-2 is expressed at high levels in cardiac muscle and functions to provide linkages between the extracellular matrix and actin cytoskeleton at costamere structures to transduce force laterally.[5]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171914Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052698Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Talin 2".