TP53BP2

TP53BP2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTP53BP2, 53BP2, ASPP2, BBP, P53BP2, PPP1R13A, tumor protein p53 binding protein 2
External IDsOMIM: 602143; MGI: 2138319; HomoloGene: 3959; GeneCards: TP53BP2; OMA:TP53BP2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001031685
NM_005426

NM_173378

RefSeq (protein)

NP_001026855
NP_005417

NP_775554

Location (UCSC)Chr 1: 223.78 – 223.85 MbChr 1: 182.24 – 182.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Apoptosis-stimulating of p53 protein 2 (ASPP2) also known as Bcl2-binding protein (Bbp) and tumor suppressor p53-binding protein 2 (p53BP2) is a protein that in humans is encoded by the TP53BP2 gene.[5][6][7] Multiple transcript variants encoding different isoforms have been found for this gene.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143514Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026510Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Naumovski L, Cleary ML (Aug 1996). "The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M". Mol Cell Biol. 16 (7): 3884–92. doi:10.1128/MCB.16.7.3884. PMC 231385. PMID 8668206.
  6. ^ Iwabuchi K, Bartel PL, Li B, Marraccino R, Fields S (Jul 1994). "Two cellular proteins that bind to wild-type but not mutant p53". Proc Natl Acad Sci U S A. 91 (13): 6098–102. Bibcode:1994PNAS...91.6098I. doi:10.1073/pnas.91.13.6098. PMC 44145. PMID 8016121.
  7. ^ "Entrez Gene: TP53BP2 tumor protein p53 binding protein, 2".