TRIM22

TRIM22
Identifiers
Aliases	TRIM22, GPSTAF50, RNF94, STAF50, tripartite motif containing 22
External IDs	OMIM: 606559; HomoloGene: 48399; GeneCards: TRIM22; OMA:TRIM22 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	5,737,089 bp
RNA expression pattern
	Top expressed in
	monocyte; ; spleen; ; lymph node; ; Achilles tendon; ; granulocyte; ; gallbladder; ; palpebral conjunctiva; ; appendix; ; right uterine tube; ; blood;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein-macromolecule adaptor activity; transcription corepressor activity; DNA-binding transcription factor activity; zinc ion binding; metal ion binding; protein binding; protein kinase binding; transferase activity;
Cellular component	cytoplasm; cytosol; Cajal body; nuclear speck; intracellular anatomical structure; nucleoplasm; nucleus; nuclear body; Golgi apparatus;
Biological process	regulation of transcription, DNA-templated; positive regulation of autophagy; interferon-gamma-mediated signaling pathway; protein trimerization; response to virus; positive regulation of DNA-binding transcription factor activity; transcription, DNA-templated; regulation of protein localization; positive regulation of NF-kappaB transcription factor activity; defense response to virus; protein ubiquitination; immune response; positive regulation of I-kappaB kinase/NF-kappaB signaling; viral process; negative regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	10346
	n/a
	ENSG00000132274
	n/a
	Q8IYM9
	n/a
	NM_006074; NM_001199573
	n/a
	NP_001186502; NP_006065
	n/a
	Wikidata
View/Edit Human

Tripartite motif-containing 22, also known as TRIM22, is a protein which in humans is encoded by the TRIM22 gene.^[3]^[4]^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132274 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: TRIM22 tripartite motif-containing 22".
^ Cite error: The named reference pmid7797467 was invoked but never defined (see the help page).
^ Gongora C, Tissot C, Cerdan C, Mechti N (November 2000). "The interferon-inducible Staf50 gene is downregulated during T cell costimulation by CD2 and CD28". J. Interferon Cytokine Res. 20 (11): 955–61. doi:10.1089/10799900050198390. PMID 11096452.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000132274 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: TRIM22 tripartite motif-containing 22".

[pmid7797467-4] Cite error: The named reference pmid7797467 was invoked but never defined (see the help page).

[pmid11096452-5] Gongora C, Tissot C, Cerdan C, Mechti N (November 2000). "The interferon-inducible Staf50 gene is downregulated during T cell costimulation by CD2 and CD28". J. Interferon Cytokine Res. 20 (11): 955–61. doi:10.1089/10799900050198390. PMID 11096452.

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