TRPM5

TRPM5
Identifiers
Aliases	TRPM5, LTRPC5, MTR1, transient receptor potential cation channel subfamily M member 5
External IDs	OMIM: 604600; MGI: 1861718; HomoloGene: 22818; GeneCards: TRPM5; OMA:TRPM5 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	2,444,514 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	142,648,379 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; seminal vesicula; ; body of pancreas; ; duodenum; ; metanephros; ; left lobe of thyroid gland; ; epididymis; ; right lobe of thyroid gland; ; caput epididymis; ; left adrenal cortex;
	Top expressed in
	islet of Langerhans; ; internal carotid artery; ; urethra; ; female urethra; ; male urethra; ; efferent ductule; ; external carotid artery; ; Gonadal ridge; ; vas deferens; ; intestinal villus;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated ion channel activity; ion channel activity; potassium channel activity; calcium activated cation channel activity; sodium channel activity;
Cellular component	plasma membrane; membrane; soma; dendrite; integral component of membrane;
Biological process	ion transport; sodium ion transmembrane transport; sensory perception of taste; calcium ion transmembrane transport; potassium ion transmembrane transport; cation transport; regulation of ion transmembrane transport; ion transmembrane transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	29850
	56843
	ENSG00000070985
	ENSMUSG00000009246
	Q9NZQ8
	Q9JJH7
	NM_014555
	NM_020277
	NP_055370
	NP_064673
	Wikidata
View/Edit Human	View/Edit Mouse

Transient receptor potential cation channel subfamily M member 5 (TRPM5), also known as long transient receptor potential channel 5 is a protein that in humans is encoded by the TRPM5 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000070985 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000009246 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Prawitt D, Enklaar T, Klemm G, Gärtner B, Spangenberg C, Winterpacht A, Higgins M, Pelletier J, Zabel B (January 2000). "Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression". Human Molecular Genetics. 9 (2): 203–16. doi:10.1093/hmg/9.2.203. PMID 10607831.
^ Clapham DE, Julius D, Montell C, Schultz G (December 2005). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacological Reviews. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100. S2CID 17936350.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000070985 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000009246 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10607831-5] Prawitt D, Enklaar T, Klemm G, Gärtner B, Spangenberg C, Winterpacht A, Higgins M, Pelletier J, Zabel B (January 2000). "Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression". Human Molecular Genetics. 9 (2): 203–16. doi:10.1093/hmg/9.2.203. PMID 10607831.

[pmid16382100-6] Clapham DE, Julius D, Montell C, Schultz G (December 2005). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacological Reviews. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100. S2CID 17936350.

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