TRPV6

TRPV6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2RFA
Identifiers
Aliases	TRPV6, ABP/ZF, CAT1, CATL, ECAC2, HSA277909, LP6728, ZFAB, transient receptor potential cation channel subfamily V member 6, HRPTTN
External IDs	OMIM: 606680; MGI: 1927259; HomoloGene: 56812; GeneCards: TRPV6; OMA:TRPV6 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	142,885,745 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	41,613,339 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; duodenum; ; placenta; ; prostate; ; islet of Langerhans; ; gallbladder; ; skin of abdomen; ; primary visual cortex; ; salivary gland; ; skin of leg;
	Top expressed in
	seminal vesicula; ; duodenum; ; lip; ; lacrimal gland; ; cervix; ; parotid gland; ; conjunctival fornix; ; medullary collecting duct; ; embryo; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ion channel activity; protein binding; calmodulin binding; calcium channel activity; metal ion binding;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	ion transport; calcium ion transport; regulation of calcium ion-dependent exocytosis; response to calcium ion; calcium ion transmembrane transport; transmembrane transport; calcium ion homeostasis; calcium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	55503
	64177
	ENSG00000276971; ENSG00000165125
	ENSMUSG00000029868
	Q9H1D0
	Q91WD2
	NM_018646; NM_014274
	NM_022413
	NP_061116
	NP_071858
	Wikidata
View/Edit Human	View/Edit Mouse

TRPV6 is a membrane calcium (Ca²⁺) channel protein which is particularly involved in the first step in Ca²⁺absorption in the intestine.

^ ^a ^b ^c ENSG00000165125 GRCh38: Ensembl release 89: ENSG00000276971, ENSG00000165125 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029868 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] ENSG00000165125 GRCh38: Ensembl release 89: ENSG00000276971, ENSG00000165125 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029868 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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