TSPAN8

TSPAN8
Identifiers
Aliases	TSPAN8, CO-029, TM4SF3, tetraspanin 8
External IDs	OMIM: 600769; MGI: 2384918; HomoloGene: 20968; GeneCards: TSPAN8; OMA:TSPAN8 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	71,441,898 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	115,685,798 bp
RNA expression pattern
	Top expressed in
	mucosa of colon; ; mucosa of sigmoid colon; ; jejunal mucosa; ; mucosa of transverse colon; ; mucosa of ileum; ; rectum; ; duodenum; ; pancreatic ductal cell; ; bronchial epithelial cell; ; gallbladder;
	Top expressed in
	seminal vesicula; ; mucous cell of stomach; ; epithelium of stomach; ; left colon; ; pyloric antrum; ; crypt of lieberkuhn of small intestine; ; Paneth cell; ; migratory enteric neural crest cell; ; right lung lobe; ; ileum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	integrin binding; protein binding;
Cellular component	integral component of membrane; integral component of plasma membrane; extracellular exosome; membrane; cell surface;
Biological process	cell surface receptor signaling pathway; negative regulation of blood coagulation; spermatogenesis; regulation of gene expression;
	Sources:Amigo / QuickGO
Orthologs
	7103
	216350
	ENSG00000127324
	ENSMUSG00000034127
	P19075
	Q8R3G9
	NM_004616; NM_001369760
	NM_001168679; NM_001168680; NM_146010
	NP_004607; NP_001356689
	NP_001162150; NP_001162151; NP_666122
	Wikidata
View/Edit Human	View/Edit Mouse

Tetraspanin-8 is a protein that in humans is encoded by the TSPAN8 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000127324 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034127 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Szala S, Kasai Y, Steplewski Z, Rodeck U, Koprowski H, Linnenbach AJ (September 1990). "Molecular cloning of cDNA for the human tumor-associated antigen CO-029 and identification of related transmembrane antigens". Proceedings of the National Academy of Sciences of the United States of America. 87 (17): 6833–7. Bibcode:1990PNAS...87.6833S. doi:10.1073/pnas.87.17.6833. PMC 54632. PMID 2395876.
^ "Entrez Gene: TSPAN8 tetraspanin 8".