Tachykinin receptor 3

TACR3
Identifiers
Aliases	TACR3, HH11, NK-3R, NK3R, NKR, TAC3RL, Tachykinin receptor 3, TAC3R, NK3
External IDs	OMIM: 162332; MGI: 892968; HomoloGene: 824; GeneCards: TACR3; OMA:TACR3 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	103,719,985 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	134,640,340 bp
RNA expression pattern
	Top expressed in
	hypothalamus; ; C1 segment; ; prefrontal cortex; ; amygdala; ; urinary bladder; ; substantia nigra; ; ventricular zone; ; corpus callosum; ; Brodmann area 9; ; primary visual cortex;
	Top expressed in
	iris; ; ventral tegmental area; ; substantia nigra; ; vestibular sensory epithelium; ; stria vascularis; ; lumbar subsegment of spinal cord; ; lateral hypothalamus; ; Gonadal ridge; ; cornea; ; adrenal cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	tachykinin receptor activity; G protein-coupled receptor activity; signal transducer activity; protein binding;
Cellular component	cytoplasm; integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; dendrite membrane; neuronal cell body membrane; nucleus; sperm midpiece;
Biological process	response to estradiol; human ageing; hyperosmotic salinity response; regulation of feeding behavior; regulation of dopamine metabolic process; positive regulation of heart rate; response to morphine; positive regulation of blood pressure; signal transduction; positive regulation of uterine smooth muscle contraction; response to cocaine; tachykinin receptor signaling pathway; positive regulation of flagellated sperm motility; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	6870
	21338
	ENSG00000169836
	ENSMUSG00000028172
	P29371
	P47937
	NM_001059
	NM_021382
	NP_001050
	NP_067357
	Wikidata
View/Edit Human	View/Edit Mouse

Tachykinin receptor 3, also known as TACR3, is a protein which in humans is encoded by the TACR3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000169836 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028172 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Huang RR, Cheung AH, Mazina KE, Strader CD, Fong TM (Apr 1992). "cDNA sequence and heterologous expression of the human neurokinin-3 receptor". Biochemical and Biophysical Research Communications. 184 (2): 966–72. doi:10.1016/0006-291X(92)90685-E. PMID 1374246.
^ "Entrez Gene: TACR3 tachykinin receptor 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000169836 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028172 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1374246-5] Huang RR, Cheung AH, Mazina KE, Strader CD, Fong TM (Apr 1992). "cDNA sequence and heterologous expression of the human neurokinin-3 receptor". Biochemical and Biophysical Research Communications. 184 (2): 966–72. doi:10.1016/0006-291X(92)90685-E. PMID 1374246.

[entrez-6] "Entrez Gene: TACR3 tachykinin receptor 3".

[1]

[2]

[3]

[4]

[5]

[6]