Talkback or talk back may refer to:
- Talkback (album), a 1983 album by the Canadian band the Spoons
- Talk Back (Kembe X album), 2016
- Talkback, an alternate name for Marvel Comics superhero Chase Stein
- Talkback (recording), an audio system used in recording studios for communications
- Talkback (television production), an audio system used in TV shows
- TalkBack Reader Response System, talkback system for internet reader response
- Talk radio, radio format
- Talkback (production company), a British television production company which merged with Thames Television
- Talkback Thames, a company resulting from the merger of Talkback Productions and Thames Television
- Google TalkBack, an accessibility service on Android