Termination factor

In molecular biology, a termination factor is a protein that mediates the termination of RNA transcription by recognizing a transcription terminator and causing the release of the newly made mRNA. This is part of the process that regulates the transcription of RNA to preserve gene expression integrity and are present in both eukaryotes and prokaryotes, although the process in bacteria is more widely understood.[1] The most extensively studied and detailed transcriptional termination factor is the Rho (ρ) protein of E. coli.[2]

  1. ^ Lodish H, Berk A, Zipursky SL, et al. (2000). Molecular Cell Biology 4th edition. New York: W. H. Freeman.
  2. ^ Boudvillain M, Figueroa-Bossi N, Bossi L (April 2013). "Terminator still moving forward: expanding roles for Rho factor". Current Opinion in Microbiology. 16 (2): 118–24. doi:10.1016/j.mib.2012.12.003. PMID 23347833.