Tetrachloroethylene

Tetrachloroethylene
Tetrachloroethylene
Tetrachloroethylene
Tetrachloroethylene
Tetrachloroethylene
  Carbon, C
  Chlorine, Cl
Names
Preferred IUPAC name
Tetrachloroethene
Other names
Carbon bichloride; Carbon dichloride (Carboneum Dichloratum); Dicarbon tetrachloride;[1] Ethylene tetrachloride; Perchlor; Perchloroethene; Perchloroethylene; Chlorethose[2]
Identifiers
3D model (JSmol)
Abbreviations PCE; Perc; Per
1304635
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.004.388 Edit this at Wikidata
EC Number
  • 204-825-9
101142
KEGG
RTECS number
  • KX3850000
UNII
UN number 1897
  • InChI=1S/C2Cl4/c3-1(4)2(5)6 checkY
    Key: CYTYCFOTNPOANT-UHFFFAOYSA-N checkY
  • InChI=1/C2Cl4/c3-1(4)2(5)6
    Key: CYTYCFOTNPOANT-UHFFFAOYAO
  • ClC(Cl)=C(Cl)Cl
Properties
C2Cl4
Molar mass 165.82 g/mol
Appearance Clear, very refractive, colorless liquid
Odor Mild, sharp and sweetish[3]
Density 1.622 g/cm3
Melting point −22.0 to −22.7 °C (−7.6 to −8.9 °F; 251.2 to 250.5 K)
Boiling point 121.1 °C (250.0 °F; 394.2 K)
0.15 g/L (25 °C)
Vapor pressure 14 mmHg (20 °C)[3]
−81.6·10−6 cm3/mol
1.505
Viscosity 0.89 cP at 25 °C
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Inhalation of vapours can cause anaesthesia and respiratory irritation. Causes irritation in contact with skin and eyes with no residual injury.
GHS labelling:
GHS08: Health hazardGHS09: Environmental hazard
Warning
H351, H411
P201, P202, P273, P281, P308+P313, P391, P405, P501
NFPA 704 (fire diamond)
Flash point Not flammable
Lethal dose or concentration (LD, LC):
3420 mg/kg (oral, rat)[4]
2629 mg/kg (oral, rat), >10000 mg/kg (dermal, rat)[5]
4000 ppm (rat, 4 hr)
5200 ppm (mouse, 4 hr)
4964 ppm (rat, 8 hr)[6]
NIOSH (US health exposure limits):
PEL (Permissible)
TWA 100 ppm
C 200 ppm (for 5 minutes in any 3-hour period), with a maximum peak of 300 ppm[3]
REL (Recommended)
Ca Minimize workplace exposure concentrations.[3]
IDLH (Immediate danger)
Ca [150 ppm][3]
Safety data sheet (SDS) External MSDS
Related compounds
Related analogous organohalides
Tetrafluoroethylene
Tetrabromoethylene
Tetraiodoethylene
Related compounds
Trichloroethylene
Dichloroethylene
1,1,2,2-Tetrachloroethane
Carbon tetrachloride
Supplementary data page
Tetrachloroethylene (data page)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Tetrachloroethylene, also known as perchloroethylene[a] or under the systematic name tetrachloroethene, and abbreviations such as perc (or PERC), and PCE, is a chlorocarbon with the formula Cl2C=CCl2. It is a non-flammable, stable, colorless and heavy liquid widely used for dry cleaning of fabrics, hence it is sometimes called "dry-cleaning fluid". It also has its uses as an effective automotive brake cleaner. It has a mild sweet, sharp odor, detectable by most people at a concentration of 50 ppm.[8]

Tetrachloroethylene is regarded as a toxin, a human health hazard, and an environmental hazard.[7][9] In 2020, the United States Environmental Protection Agency stated that "tetrachloroethylene exposure may harm the nervous system, liver, kidneys, and reproductive system, and may be harmful to unborn children", and reported that numerous toxicology agencies regard it as a carcinogen.[10]

  1. ^ C. Chabrie "General Method for the Preparation of Carbon Fluorides" in Journal - Chemical Society, London. (1890). UK: Chemical Society.
  2. ^ Justus Liebigs Annalen der Chemie. (1845). Germany: Verlag Chemie. Page 277
  3. ^ a b c d e NIOSH Pocket Guide to Chemical Hazards. "#0599". National Institute for Occupational Safety and Health (NIOSH).
  4. ^ Sigma Aldrich Tetrachloroethylene MSDS
  5. ^ Fischer Scientific Tetrachloroethylene MSDS
  6. ^ "Tetrachloroethylene". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  7. ^ a b "Compound Summary: Tetrachloroethylene". PubChem, US National Library of Medicine. 21 September 2024. Retrieved 24 September 2024.
  8. ^ Browning, Ethel (1953). "Perchloroethylene". Toxicity of Industrial Organic Solvents. Chemical Publishing. pp. 182–185.
  9. ^ US Agency for Toxic Substances and Disease Registry (June 2019). "Toxicological Profile for Tetrachloroethylene". US National Library of Medicine. Retrieved 23 September 2024.
  10. ^ "Public Health Statement for Tetrachloroethylene (PERC)". US Environmental Protection Agency. 22 June 2020. Retrieved 23 September 2024.


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