The Principles and Practice of Medicine: Designed for the Use of Practitioners and Students of Medicine is a medical textbook by Sir William Osler. It was first published in 1892 by D. Appleton & Company, while Osler was professor of Medicine at Johns Hopkins University. The book established Osler as the world's leading authority in the teaching of modern medicine.[1]
The text was translated into French, German, Russian, Portuguese, Spanish and Chinese, and for over 40 years it was the world's most significant medical textbook.[2]