Thiazepines are substituted thiepins, with a nitrogen replacing a carbon in the seven-membered heterocyclic compound.[1] Depending on the location of the nitrogen, one distinguishes 1,3-thiazepine and 1,4-thiazepine.[1]
Benzothiazepines have a single benzene attached to the ring, while dibenzothiazepines have two. Diltiazem, a benzothiazepine, is a calcium channel blocker intermediate in properties between verapamil and the dihydropyridines. It is used to treat variant angina (Prinzmetal's angina), either naturally occurring or drug-induced and stable angina.
- ^ a b "MeSH Browser". meshb.nlm.nih.gov. Retrieved 2022-11-24.