Thogotovirus

Thogotovirus
Electron micrograph of Bourbon virus (scale bar: 100 nm)
Electron micrograph of Bourbon virus (scale bar: 100 nm)
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Insthoviricetes
Order: Articulavirales
Family: Orthomyxoviridae
Genus: Thogotovirus
Species
Synonyms[1]

Thogoto-like viruses

Thogotovirus is a genus of enveloped RNA viruses, one of seven genera in the virus family Orthomyxoviridae. Their single-stranded, negative-sense RNA genome has six or seven segments. Thogotoviruses are distinguished from most other orthomyxoviruses[3] by being arboviruses – viruses that are transmitted by arthropods, in this case usually ticks. Thogotoviruses can replicate in both tick cells and vertebrate cells; one subtype has also been isolated from mosquitoes. A consequence of being transmitted by blood-sucking vectors is that the virus must spread systemically in the vertebrate host – unlike influenza viruses, which are transmitted by respiratory droplets and are usually confined to the respiratory system.[4]

The genus contains the species Thogoto thogotovirus and Dhori virus (DHOV), and the latter's subtype Batken virus, as well as the species or strains Araguari virus, Aransas Bay virus (ABV), Bourbon virus, Jos virus (JOSV) and Upolu virus (UPOV), which have yet to be confirmed by the International Committee on Taxonomy of Viruses (ICTV). A wide range of mammals are infected by members of the genus; some types also infect birds. THOV causes disease in livestock. THOV, DHOV and Bourbon virus can infect humans, and have occasionally been associated with human disease.

  1. ^ Pringle, C. R. (1996). "Virus Taxonomy 1996 - A Bulletin from the Xth International Congress of Virology in Jerusalem" (PDF). Arch Virol. 141 (11): 2251–2256. doi:10.1007/BF01718231. PMC 7086844. PMID 8992952. Retrieved 4 June 2019.
  2. ^ Cite error: The named reference Bussetti was invoked but never defined (see the help page).
  3. ^ Members of the recently ratified genus Quaranjavirus are also transmitted by ticks.[2]
  4. ^ Cite error: The named reference Kochs was invoked but never defined (see the help page).