Tityus stigmurus toxin 1 (Tst1) is a neurotoxin found in the venom of the Brazilian scorpion, Tityus stigmurus. It acts on voltage-gated sodium channels (Navs), altering opening and inactivation voltages, recovery from inactivation, and overall current flow.
Superfamily | Scorpion toxin |
Family | NaScTx (Sodium channel toxins) |
Subfamily | β-toxin |
Mature protein amino acid sequence | GKEGYLMDHEGCKLSCFIRPSGYCGRECTLKKGSSGYCAWPACYCYGLPNWVKVWDRATNKC |