Tlacuilolxochtzin | |
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| Princess of Ecatepec | |
| Born | Mexico |
| Spouse(s) | Tezozomoctli Acolnahuacatl |
| Issue | Diego de Alvarado Huanitzin Don Francisco Matlaccoatzin Don Carlos Oquiztzin |
| Father | Matlaccoatzin |
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| Aztec Empire |
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Tlacuilolxochtzin (Nahuatl: tɬakʷilolʃotʃtsin) was an Aztec noblewoman of very noble heritage, Lady of Ecatepec and sister of queen Tlapalizquixochtzin.