Tlatelolco (Classical Nahuatl: Tlatelōlco [tɬateˈloːɬko], or Tlatilōlco, from tlalli - land; telolli - hill; co - place; lit. 'In the little hill of land') is an area now within the Cuauhtémoc borough of Mexico City, centered on the Plaza de las Tres Culturas (Square of Three Cultures). Its archeological history extends to remains from the 15th and 16th centuries, as well as more recent colonial structures.
The square is bounded by an excavated Aztec archaeological site, the 16th century college church designed by Fray Juan de Torquemada and dedicated to St James the Great (known as Colegio de Santa Cruz de Tlatelolco), the remains of a former Franciscan convent to which was formerly attached the Colegio de Santa Cruz de Tlatelolco, and an office complex that was used by the Ministry of Foreign Relations and is now the property of the National Autonomous University of Mexico.