Tolmetin

Tolmetin

Clinical data
Trade names	Tolectin
AHFS/Drugs.com	Monograph
MedlinePlus	a681033
Routes of administration	By mouth
ATC code	M01AB03 (WHO) M02AA21 (WHO)
Legal status
Legal status	AU: S4 (Prescription only)
Pharmacokinetic data
Elimination half-life	1-2 hours, next phase up to 5 hours
Identifiers
IUPAC name [1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid
CAS Number	26171-23-3 Y
PubChem CID	5509
IUPHAR/BPS	7311
DrugBank	DB00500 Y
ChemSpider	5308 Y
UNII	D8K2JPN18B
KEGG	D02355 Y
ChEBI	CHEBI:71941 N
ChEMBL	ChEMBL1020 Y
CompTox Dashboard (EPA)	DTXSID2043951
ECHA InfoCard	100.043.164
Chemical and physical data
Formula	C15H15NO3
Molar mass	257.289 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(c1ccc(n1C)CC(=O)O)c2ccc(cc2)C
InChI InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18) Y Key:UPSPUYADGBWSHF-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Tolmetin (/ˈtɒlmətɪn/) is a nonsteroidal anti-inflammatory drug (NSAID) of the heterocyclic acetic acid derivative class.

Tolmetin was originally approved by the US FDA in 1976. It is available internationally.^[1]

It is used primarily to reduce hormones that cause pain, swelling, tenderness, and stiffness in conditions such as osteoarthritis and rheumatoid arthritis, including juvenile rheumatoid arthritis. In the United States it was marketed as Tolectin and comes as a tablet or capsule.