Tricine

Not to be confused with Tricin.
Tricine
Skeletal formula of tricine
Names
IUPAC name
N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]glycine
Systematic IUPAC name
{[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}acetic acid
Other names
Tricine
N-(Tri(hydroxymethyl)methyl)glycine
Identifiers
3D model (JSmol)
1937804
ChEBI
ChemSpider
ECHA InfoCard 100.024.721 Edit this at Wikidata
EC Number
  • 227-193-6
3688
MeSH tricine
UNII
  • InChI=1S/C6H13NO5/c8-2-6(3-9,4-10)7-1-5(11)12/h7-10H,1-4H2,(H,11,12) checkY
    Key: SEQKRHFRPICQDD-UHFFFAOYSA-N checkY
  • O=C(O)CNC(CO)(CO)CO
Properties
C6H13NO5
Molar mass 179.172 g·mol−1
Appearance White crystals
89.6 g L−1 (at 20 °C)
UV-vis (λmax) 260 nm
Absorbance 0.03
Related compounds
Related compounds
 Milacemide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Tricine is an organic compound that is used in buffer solutions. The name tricine comes from tris and glycine, from which it was derived.[1] It is a white crystalline powder that is moderately soluble in water. It is a zwitterionic amino acid that has a pKa1 value of 2.3 at 25 °C, while its pKa2 at 20 °C is 8.15. Its useful buffering range of pH is 7.4-8.8. Along with bicine, it is one of Good's buffering agents. Good first prepared tricine to buffer chloroplast reactions.

  1. ^ Good, N.E., et al., Biochemistry, v. 5, 467 (1966).