Tropical sprue

Tropical sprue
Other namesPostinfectious tropical malabsorption[1]
SpecialtyGastroenterology Edit this on Wikidata
SymptomsDiarrhoea, abdominal pain, weight loss
ComplicationsMalabsorption, anaemia
Diagnostic methodIntestinal histology
Differential diagnosisCoeliac disease, environmental enteropathy
TreatmentAntibiotics, folate replacement

Tropical sprue is a malabsorption disease commonly found in tropical regions, marked with abnormal flattening of the villi and inflammation of the lining of the small intestine.[1][2] It differs significantly from coeliac sprue. It appears to be a more severe form of environmental enteropathy.[3][4]

  1. ^ a b Wanke, Christine A. (2015). "Tropical Sprue: enteropathy". In Bennett, John E.; Dolin, Raphael; Blaser, Martin J. (eds.). Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases (8 ed.). pp. 1297–1301. doi:10.1016/B978-1-4557-4801-3.00104-1. PMC 7151975.
  2. ^ Ramakrishna BS, Venkataraman S, Mukhopadhya A (2006). "Tropical malabsorption". Postgrad Med J. 82 (974): 779–87. doi:10.1136/pgmj.2006.048579. PMC 2653921. PMID 17148698.
  3. ^ Korpe PS, Petri WA (2012). "Environmental enteropathy: critical implications of a poorly understood condition". Trends Mol Med. 18 (6): 328–36. doi:10.1016/j.molmed.2012.04.007. PMC 3372657. PMID 22633998.
  4. ^ Ghoshal UC, Srivastava D, Verma A, Ghoshal U (2014). "Tropical sprue in 2014: the new face of an old disease". Curr Gastroenterol Rep. 16 (6): 391. doi:10.1007/s11894-014-0391-3. PMC 7088824. PMID 24781741.