Tugaloo (Dugiluyi (ᏚᎩᎷᏱ)) was a Cherokee town located on the Tugaloo River, at the mouth of Toccoa Creek. It was south of Toccoa and Travelers Rest State Historic Site in present-day Stephens County, Georgia, United States. Cultures of ancient indigenous peoples had occupied this area, and those of the South Appalachian Mississippian culture built a platform mound and village here. It was an administrative and ceremonial center for them.
About six miles upriver was Estatoe, another historic Cherokee town in this area. (Other historic towns named Estatoe were identified in both western South Carolina and North Carolina.) Both the historic and prehistoric sites of Estatoe and Tugaloo were inundated by the creation of Lake Hartwell above Hartwell Dam.