U.S. Route 220

U.S. Route 220
Route information
Auxiliary route of US 20
Length	678 mi[citation needed] (1,091 km)
Existed	November 11, 1926[1]–present
Major junctions
South end	US 1 in Rockingham, NC
Major intersections	I-73 / I-74 near Candor, NC I-85 / US 421 in Greensboro, NC I-40 in Greensboro, NC I-81 near Roanoke, VA I-64 / US 60 near Clifton Forge, VA I-68 / US 40 in Cumberland, MD I-70 / I-76 / Penna Turnpike near Bedford, PA I-99 from Bedford, PA to Bellefonte, PA I-80 near Bellefonte, PA
North end	I-86 / NY 17 / Southern Tier Expressway at the PA-NY state line in South Waverly, PA
Location
Country	United States
States	North Carolina, Virginia, West Virginia, Maryland, Pennsylvania
Highway system
United States Numbered Highway System List Special Divided

U.S. Route 220 (US 220) is a spur route of US 20. It runs in a north–south layout in the eastern United States, unlike its parent route as well as conventionally even-numbered highways, which run east-west. US 220 extends for 678 miles (1,091 km) from an intersection with US 1 in Rockingham, North Carolina, to its interchange with the Southern Tier Expressway (Interstate 86 and New York State Route 17) in South Waverly, Pennsylvania. Some sections of the route are part of the Appalachian Development Highway System's Corridor O as well as I-73 in North Carolina. US 220 is designated as a spur route of US 20 but the route does not intersect US 20 or connect to other spurs of US 20.

US 220 was assigned in 1926 as part of the establishment of the U.S. Highway System. At the time, it extended from Cumberland, Maryland, to the New York–Pennsylvania border at Lawrenceville, Pennsylvania. One year later, US 220 was realigned north of Williamsport, Pennsylvania, to connect to the New York state line at South Waverly; this supplanted most of what was originally designated U.S. Route 711. US 220 was extended south through Virginia by 1935 and to its current southern terminus by 1941.